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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE1
All Species:
13.33
Human Site:
S444
Identified Species:
32.59
UniProt:
Q8IWY4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWY4
NP_766638.2
988
107910
S444
H
T
L
F
V
P
D
S
E
N
S
Y
V
L
S
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
P452
L
L
P
T
S
V
S
P
R
V
S
L
H
C
G
Rhesus Macaque
Macaca mulatta
XP_001108689
995
108761
S445
H
T
L
F
V
P
D
S
E
N
S
Y
V
L
S
Dog
Lupus familis
XP_538874
1009
111038
S455
R
A
R
F
L
P
E
S
E
N
G
F
T
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZL8
1018
111587
S474
H
S
L
F
M
P
D
S
E
S
S
Y
I
L
S
Rat
Rattus norvegicus
O88281
1574
165428
G534
T
C
D
D
C
R
N
G
G
T
C
F
P
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
S387
F
L
P
D
N
V
S
S
R
V
L
L
R
C
V
Chicken
Gallus gallus
O73775
704
78120
D217
P
D
G
V
N
C
E
D
I
N
E
C
I
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
A467
Q
V
H
I
S
S
G
A
E
D
S
Y
T
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
S389
R
R
V
T
R
Q
L
S
K
T
I
N
Q
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.3
89.5
64.8
N.A.
89.2
22.4
N.A.
55.9
21.2
N.A.
64.6
N.A.
N.A.
N.A.
N.A.
43.3
Protein Similarity:
100
76.6
91.6
76.9
N.A.
92.6
31.8
N.A.
67.9
32.7
N.A.
77.2
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
6.6
100
40
N.A.
73.3
0
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
66.6
N.A.
100
13.3
N.A.
6.6
20
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
10
10
0
0
0
0
10
10
0
20
0
% C
% Asp:
0
10
10
20
0
0
30
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
20
0
50
0
10
0
0
0
0
% E
% Phe:
10
0
0
40
0
0
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
10
10
0
10
0
0
10
20
% G
% His:
30
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
0
10
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% K
% Leu:
10
20
30
0
10
0
10
0
0
0
10
20
0
30
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
10
0
0
40
0
10
0
0
0
% N
% Pro:
10
0
20
0
0
40
0
10
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
10
% Q
% Arg:
20
10
10
0
10
10
0
0
20
0
0
0
10
0
0
% R
% Ser:
0
10
0
0
20
10
20
60
0
10
50
0
0
0
40
% S
% Thr:
10
20
0
20
0
0
0
0
0
20
0
0
20
10
10
% T
% Val:
0
10
10
10
20
20
0
0
0
20
0
0
20
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _